The Arizona Cardinals visit the Los Angeles Rams on Sunday in a Week 6 NFC West matchup that has Los Angeles as a heavy favorite. Kalshi traders have the Rams at 87% to win and the Cardinals at just 13%, reflecting the gap between a 2-3 Rams team that entered 2026 as a Super Bowl favorite and a 1-4 Cardinals team in the middle of a rebuild.
Arizona arrives on a four-game losing streak after trading receiver Marvin Harrison Jr. to Houston on Oct. 12, while Los Angeles is playing on a short week after Monday night but without Myles Garrett, who is on injured reserve with a knee injury.
For informational purposes only. Not financial advice. See full disclaimer below. Kalshi is not affiliated with the NFL.
When and where do the Cardinals play the Rams in Week 6 of the 2026 season?
The Cardinals and Rams kick off Sunday, Oct. 18, at 4:05 p.m. ET (1:05 p.m. PT) at SoFi Stadium in Inglewood, Calif.
Who is favored to win the Cardinals vs. Rams Week 6 game?
Arizona is 1-4 after a 45-21 home loss to Detroit on Oct. 12, the same day they traded receiver Marvin Harrison Jr. to Houston. As of this writing, tight end Hunter Long (knee) is on injured reserve.
Los Angeles is 2-3 and playing on a short week after Monday night. As of this writing, Garrett (knee) is on injured reserve, and Sean McVay has said he is on track but not expected to return to practice next week.
Kalshi power rankings
According to Kalshi's 2026 NFL power rankings, Los Angeles enters as the No. 7 team in the league with a Power Score of 70.8 and a 72% playoff qualification price, while Arizona ranks 29th with a Power Score of 9.4 and a 2% playoff price, a 22-spot gap heading into the NFC West matchup.
What the Kalshi market says
Kalshi traders have the Rams at 87% to win and the Cardinals at 13%.
What is the point spread for Cardinals vs. Rams in Week 6?
As of this writing, Kalshi traders have the Rams winning by more than 12.5 points at 49%.
What is the projected point total?
As of this writing, Kalshi traders have the game finishing over 51.5 total points at 50%.
What is the biggest storyline in the Cardinals vs. Rams Week 6 game?
LaFleur returns to SoFi Stadium to face the team he coordinated for three seasons, with Arizona on a four-game losing streak and a Rams team that entered the year as a Super Bowl favorite sitting at 2-3. Stafford leads the NFL in passing yards through five weeks.
What are the Cardinals' and Rams' expectations entering the 2026 season?
Arizona Cardinals: Arizona entered 2026 in a rebuild after finishing in a four-way tie for the league's worst record, with a new coach and Brissett replacing Murray at quarterback. Trey McBride set the NFL record for tight end receptions in 2025 with 126.
Los Angeles Rams: Los Angeles entered 2026 as the first team to carry both the reigning MVP in Stafford and the reigning Defensive Player of the Year in Garrett, and as a Super Bowl favorite. The 2-3 start has been a setback.
Conclusion
Kalshi traders have Los Angeles as a heavy favorite at 87%, against an Arizona team on a four-game losing streak. The swing factor is whether Arizona's offense can move the ball against a Rams defense playing without Garrett. Kalshi's prices for Cardinals vs. Rams will keep moving as the week goes.
What are the score predictions for Cardinals vs. Rams in Week 6? As of this writing, Kalshi traders have the game finishing over 51.5 total points at 50%.
What is the spread for Cardinals vs. Rams in Week 6? As of this writing, Kalshi traders have the Rams winning by more than 12.5 points at 49%.
Who is favored to win, Cardinals or Rams? As of this writing, Kalshi traders have the Rams at 87% to win and the Cardinals at 13%.
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