Josh Allen has seen this movie before, and it did not end well. The Bills visit SoFi Stadium on Monday, Oct. 12, for an 8:15 p.m. ET rematch with the Rams, who edged Buffalo 44-42 in December 2024. Kalshi traders have the Rams at 62% to win and the Bills at 39%.
For informational purposes only. Not financial advice. See full disclaimer below. Kalshi is not affiliated with the NFL.
Who is favored to win the Bills vs. Rams Week 5 game?
The Rams beat the Eagles 24-20 in Week 4, the game in which receiver Puka Nacua returned after missing two games. Tight end Terrance Ferguson went on injured reserve, and, as of this writing, McVay is hopeful that defensive end Aaron Donald, cornerback Jaylen Watson and tight end Colby Parkinson can play.
The Bills are 3-1 under head coach Joe Brady with Josh Allen at quarterback. As of this writing, receiver DJ Moore, defensive lineman Ed Oliver and cornerback Dee Alford did not practice Thursday, while cornerback Christian Benford and defensive lineman Landon Jackson were limited.
Buffalo enters as the No. 4 team in the league with a Power Score of 86.2, and Kalshi traders have the Bills at 89% to make the playoffs. Los Angeles ranks 6th with a Power Score of 78.0, and Kalshi traders have the Rams at 74% to qualify, a 2-spot gap heading into SoFi Stadium.
What the Kalshi market says
Kalshi traders have the Rams at 62% to win and the Bills at 39%.
What is the point spread for Bills vs. Rams in Week 5?
As of this writing, Kalshi traders have the Rams at 48% to win by more than 3.5 points.
What is the projected point total?
As of this writing, Kalshi traders have the game at 52% to finish over 54.5 total points.
What is the biggest storyline in the Bills vs. Rams Week 5 game?
The sharpest storyline is the matchup of Allen and Stafford, who last met in a 44-42 Rams win at SoFi Stadium in December 2024. Allen became the first player in the Super Bowl era to run for three touchdowns and pass for three in a game that night. Stafford has thrown for 1,189 yards, six touchdowns and six interceptions through four games this season.
What are the Bills' and Rams' expectations entering the 2026 season?
Buffalo Bills: Kalshi traders have the Bills at 89% to reach the playoffs.
Los Angeles Rams: Kalshi traders have the Rams at 74% to reach the playoffs.
Conclusion
Kalshi traders have Los Angeles as a modest favorite at 62% to win, and the swing factor is whether Buffalo's defense can slow Stafford and Nacua while Allen keeps pace. Kalshi's prices for Bills vs. Rams will keep moving as kickoff approaches.
What are the score predictions for Bills vs. Rams? As of this writing, Kalshi traders have the game at 52% to finish over 54.5 total points.
What is the spread for Bills vs. Rams? As of this writing, Kalshi traders have the Rams at 48% to win by more than 3.5 points.
Who is favored to win, Bills or Rams? As of this writing, Kalshi traders have the Rams at 62% to win and the Bills at 39%.
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