Cowboys vs. Cardinals odds and predictions: Dallas, Arizona both priced at 50%

The Dallas Cowboys travel to State Farm Stadium to face the Arizona Cardinals on Saturday, with kickoff set for 10:00 p.m. ET on NFL Network. The market prices Dallas at 50% and Arizona at 50%, as of this writing.

Both teams are 1-0 after preseason Week 1 wins that leaned heavily on backups, and that pattern figures to hold. Dak Prescott has not played in a preseason game in years, and Dallas coach Brian Schottenheimer has said his starters, Prescott included, will not play in the preseason at all.

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Kalshi traders call this one a coin flip, as of this writing. The even number reflects a game where both rosters are likely to be led by backups and roster-bubble players rather than the units fans will see in September.

According to Kalshi's 2026 NFL market-implied power rankings, Dallas enters as the No. 4 team in the league while Arizona ranks 29th, one of the widest gaps in this week's slate, though the rankings reflect season-long odds rather than Saturday's backup-heavy matchup.

Dallas' injury list includes tight end Princeton Fant, who tore his ACL and MCL during a run play in padded practice and will require surgery, a significant blow to the Cowboys' depth at the position.

Arizona's report is led by rookies: running back Jeremiyah Love is dealing with a high ankle sprain the team is hoping resolves in time for Week 1, while second-round guard Chase Bisontis tore his MCL in the Week 1 win over Las Vegas and is out for the season.

Prescott is not expected to play Saturday, continuing his preseason-long absence, while Arizona's Jacoby Brissett and the rest of the Cardinals' starting offense played just one series in Week 1 before giving way to the backups, a pattern first-year coach Mike LaFleur figures to repeat.

That leaves Saturday largely to each team's depth chart battles. Dallas' Sam Howell and Joe Milton III are both expected to get another look in the ongoing competition for the backup quarterback job, while Arizona continues auditioning its receiver corps behind Marvin Harrison Jr. and its offensive line depth after Bisontis' season-ending injury.

Arizona is priced at 45% to win by more than 1.5 points, as of this writing.

The total is priced at 53% to go over 37.5 points, as of this writing.

Dallas is priced at 38% to win the NFC East, as of this writing, with Philadelphia leading the division at 41%.

Arizona is priced at 2% to win the NFC West, as of this writing, with Los Angeles leading the division at 49%.

Kalshi markets now predict:

When is Dallas vs. Arizona? Saturday, August 22, 2026, at 10:00 p.m. ET.
Where is the game? State Farm Stadium in Glendale, Arizona.
How can I watch? NFL Network.
What is Kalshi traders' current number? Dallas and Arizona are both priced at 50%, a dead-even coin flip as of this writing.

Kalshi traders call this one a coin flip, pricing both teams at 50% in a game likely to be dominated by backups on both sides.

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