The Jacksonville Jaguars and Denver Broncos meet Sunday, September 20 at 4:05 p.m. ET at Empower Field at Mile High in Denver. Jacksonville enters 1-0, Denver enters 0-1. Kalshi traders have the Broncos at 57% to win and the Jaguars at 44%.

For informational purposes only. Not financial advice. See full disclaimer below. Kalshi is not affiliated with the NFL.

Who is favored to win the Jaguars-Broncos Week 2 game?

Jacksonville finished 13-4 in 2025 and won the AFC South under head coach Liam Coen, earning the No. 3 seed before losing to the Bills in the Wild Card round. Quarterback Trevor Lawrence returns after a strong finish to 2025, and the Jaguars opened 2026 with a blowout win over Cleveland behind four touchdown passes. Edge rusher B.J. Green is out for at least four games with an elbow injury, and wide receivers Jakobi Meyers (thumb) and Brian Thomas Jr. (shoulder) were both limited in practice this week, though neither carries an injury designation for Sunday.

Denver went 14-3 in 2025 and won the AFC West under head coach Sean Payton before reaching the AFC Championship Game, where the Broncos lost to the Patriots. Quarterback Bo Nix returns as the starter, and the Broncos opened 2026 with a blowout loss to Kansas City in which their defense missed 28 tackles, the most allowed in a game since at least 2018. Running back RJ Harvey (hamstring) is questionable after progressing to limited practice sessions Thursday and Friday, wide receiver Marvin Mims Jr. (foot) also missed time on a short week, and linebacker Levelle Bailey was placed on injured reserve in the preseason.

Kalshi power rankings

The Jaguars enter as the No. 7 team in the league with a Power Score of 77.6 and a 60% playoff qualification price, while the Broncos rank 17th with a Power Score of 43.1 and a 53% playoff price, a 10-spot gap heading into Sunday's game.

What the Kalshi market says

Kalshi traders have the Broncos at 57% and the Jaguars at 44% as Denver opens as a modest favorite at home.

What is the point spread for Jaguars vs. Broncos in Week 2?

Kalshi traders predict the Broncos to be favored by 3 points over the Jaguars, as of this writing.

What is the projected point total?

Kalshi traders predict a point total of 45.5 for Sunday's game, as of this writing.

What is the biggest storyline in the Jaguars-Broncos Week 2 game?

The sharpest storyline is Denver looking to bounce back from a lopsided Week 1 tackling meltdown against a Jaguars team that beat the Broncos 34-20 in their last meeting. Jacksonville will be tested by the altitude and crowd at Mile High for the first time this season.

What are the Jaguars' and Broncos' expectations entering the 2026 season?

Jacksonville Jaguars: After winning the AFC South and finishing third in the conference, the Jaguars are looking to build on Trevor Lawrence's strong finish to 2025. Jacksonville opened 2026 with a dominant win over Cleveland.

Denver Broncos: After winning the AFC West at 14-3, the Broncos are looking to shake off a rough season-opening loss to Kansas City. Denver enters Week 2 needing to clean up tackling issues on defense.

Conclusion

Kalshi traders see Denver as the modest favorite in Sunday's game, with the Broncos' Week 1 tackling issues and Jacksonville's road trip both factoring into that price. Kalshi's prices for Jaguars-Broncos will keep moving until the game ends.

What are the score predictions for Jaguars vs. Broncos? As of this writing, Kalshi traders predict a point total of 45.5.

What is the spread for Jaguars vs. Broncos? As of this writing, Kalshi traders have the Broncos favored by 3 points.

Who is favored to win, Jaguars or Broncos? As of this writing, Kalshi traders have the Broncos favored at 57% to beat the Jaguars.

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