The No. 5 ranked Indiana Hoosiers (3-0) host the Northwestern Wildcats (2-0) at Memorial Stadium in Bloomington on Friday night, with kickoff set for 8 p.m. ET on FOX. Kalshi traders have Indiana at 92% to win, as of this writing.

The game opens Big Ten play for both programs and is Northwestern's first road trip of the season. Indiana enters as the defending national champion after a 16-0 run through 2025. The Hoosiers won the last meeting 41-24 in Evanston in 2024.

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  • Matchup: Northwestern Wildcats vs. Indiana Hoosiers

  • Kickoff: Friday, Sept. 25, 2026, 8 p.m. ET

  • Venue: Memorial Stadium, Bloomington, Ind.

  • Watch: FOX

  • Kalshi traders' current number: 92% Indiana / 8% Northwestern (as of this writing)

Northwestern vs. Indiana, Friday, September 25, 2026

Indiana's price has held near or above 90% since the market opened Sept. 11, leaving Northwestern at 8% as of this writing. Nearly $970,000 has traded on the game contract. The Hoosiers have outscored their first three opponents 145-16, including back-to-back shutouts of Howard and Western Kentucky.

Northwestern listed 14 players as out on Wednesday's Big Ten availability report, including starting offensive lineman Ezomo Oratokhai and defensive end Callen Campbell, per 247Sports. Starting defensive back Braden Turner was listed as doubtful. Indiana ruled out running back Khobie Martin, receiver LeBron Bond and cornerback Carson Williams. Cornerback A.J. Harris is doubtful, and kicker Nico Radicic is questionable after missing two games with a back injury.

Indiana edge rushers Stephen Daley and Kellan Wyatt came off the availability report after previously carrying questionable tags. Both won a preliminary injunction against the NCAA on Wednesday, clearing them to play for the rest of the season.

Both quarterbacks arrive as transfers with clean records. Indiana's Josh Hoover has thrown for 649 yards and 10 touchdowns through three games. Northwestern's Aidan Chiles, formerly of Michigan State, is completing 67% of his passes, and the Wildcats forced four turnovers in last week's 41-7 win over Colorado.

Margin of Victory

Kalshi traders price Indiana winning by over 20.5 points at 50%, as of this writing.

Point Total

The market has over 49.5 combined points priced at 51%, as of this writing.

Indiana's College Football Playoff National Championship odds

Indiana is priced at 11% on Kalshi to win the College Football Playoff National Championship, fifth on the board as of this writing.

Big Ten Championship odds

Indiana is priced at 25% on Kalshi to win the Big Ten Championship, second on the conference board as of this writing. Northwestern trades below 1%.

Kalshi markets now predict:

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