No. 16 SMU travels to No. 23 Louisville on Saturday, September 19, kicking off at 3:30 p.m. ET from L&N Federal Credit Union Stadium in Louisville, Kentucky. SMU enters at 2-0, Louisville at 1-1. Kalshi traders have Louisville's win probability at 54% and SMU at 46%, as of this writing.
Saturday is the first real ACC test of the season for both programs. SMU is unbeaten after wins over Florida State and UC Davis and already has one conference win banked, while Louisville enters off a 59-13 rout of Villanova following an opening loss to Ole Miss. SMU has won both previous meetings between the schools, including a 38-6 win last season.
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Matchup: SMU vs. Louisville
Kickoff: Saturday, Sep 19, 2026, 3:30 PM ET
Venue: L&N Federal Credit Union Stadium, Louisville, Kentucky
Watch: ESPN2
Kalshi traders' current number: 54% Louisville / 46% SMU (as of this writing)
SMU vs. Louisville, Saturday, September 19, 2026
Louisville is a narrow favorite at home, with Kalshi traders pricing the Cardinals at 54% in a matchup between two of the most productive offenses in the country early this season.
Louisville is trending toward getting healthier up front, with left tackle Anwar O'Neal and Montavin Quisenberry both probable after each missed time. A returning O'Neal would let Louisville shift Lance Robinson back to center, a change the staff believes could open up the run game.
The stat matchup to watch is SMU quarterback Kevin Jennings against a Louisville defense that has already forced seven sacks through two games. Jennings has completed 76.9% of his throws for 767 yards and eight touchdowns this season, and he owns a career mark against Louisville of 697 total yards and five touchdowns with zero interceptions across two prior meetings.
Louisville enters off a 635-yard, 59-point performance against Villanova behind quarterback Lincoln Kienholz, who accounted for 374 total yards and four touchdowns in that game. SMU is allowing just 17 points per game defensively, led by safety Jimmy Wyrick's two sacks and linebacker Alexander Kilgore anchoring the middle.
Margin of victory
Kalshi traders have Louisville winning by over 2.5 points priced at 50%, as of this writing.
Point total
The total is set at 58.5 points, with the over priced at 51% on Kalshi, as of this writing.
College Football Playoff National Championship
Neither SMU nor Louisville is currently priced above 1% in the College Football Playoff National Championship market, as of this writing.
ACC Championship
Team | ACC Championship |
|---|---|
SMU | 14% |
Louisville | 6% |
SMU leads Louisville in the ACC championship market, 14% to 6%, as of this writing.
Kalshi markets now predict:
When is SMU vs. Louisville? Saturday, September 19, 2026, at 3:30 p.m. ET.
Where is the game? L&N Federal Credit Union Stadium in Louisville, Kentucky.
How can I watch? The game airs on ESPN2.
What is Kalshi traders' current number? Kalshi traders have Louisville at 54% and SMU at 46%, as of this writing.
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